Probing of an Appreciable Antimicrobial Compound Producing Lactobacillus Strain from Milk Products of Thanjavur Region, Tamil Nadu and its Enhanced Production

ABSTRACT: Lactobacillus is a heterogeneous class of lactic acid strains that synthesize bioactive compounds which contribute many health benefits to our mankind. Focusing this view, different were collected from dairy products and screened for their efficiencies against an infant diarrheal bacterial pathogen. 11 morphologically unique procured curd, yoghurt buttermilk purchased the Thanjavur region, Tamil Nadu, India. While screening on microtiter plate-based test, YMP3 revealed best antimicrobial activity human pathogenic Vibrio cholerae with 67.8±2.1% inhibition. Further, most appreciable strain was molecularly identified as apis based 16S rRNA sequencing methodology. Based growth kinetics profile, showed maximum production compound between 72 108hrs incubation. Furthermore, evidenced cultural conditions pH 6.5 35°C temperature compound. these overall observations, research stood promising baseline data enhanced investigation probiotic L. its possibilities drug development.